Description

TB-500 (Thymosin Beta-4) Research Topics:

1. Tissue Repair and Wound Healing:

   TB-500 accelerates the repair of injured tissues by promoting cell migration, differentiation, and new blood vessel formation. This peptide significantly enhances wound healing and reduces scarring (PMID: 38382158).

2. Cardiovascular Health:

   TB-500 has been shown to improve cardiac function by reducing inflammation and promoting angiogenesis (the formation of new blood vessels). It can help mediate cardioprotection, especially following myocardial infarction (PMID: 17495252).

3. Reduction of Inflammation:

   The peptide has potent anti-inflammatory properties, making it useful for reducing inflammation in various tissues, including the cardiovascular system (PMID: 34280397).

4. Hair Growth:

   TB-500 has been observed to aid in hair growth by promoting cell proliferation and angiogenesis, which improves nutrient delivery to hair follicles (PMID: 27130465).

Peer-Reviewed Studies 

• Synthesis and characterization of the N‐terminal acetylated 17‐23 fragment of thymosin beta 4 identified in TB‐500, a product suspected to possess doping potential

Esposito, S., Deventer, K., Goeman, J., Van der Eycken, J., & Van Eenoo, P. (2012)

Drug testing and analysis, 4(9), 733-738.

• Adsorption effects of the doping relevant peptides Insulin Lispro, Synachten, TB-500 and GHRP 5

Judák, P., Van Eenoo, P., & Deventer, K. (2017)

Analytical biochemistry, 537, 69-71.

Structure

Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu­lle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr­Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu­Thr-lle-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser Molecular formula: C212H350N5s01aS
Molar Mass: 4963.4408
CAS number: 77591-33-4
PubChem: CID 16132341