Description

VIP Peptide (Vasoactive Intestinal Peptide) Research Topics:

• Neuroprotective Effects:

  VIP is known to modulate neuroinflammation and promote neuronal survival through its interaction with VPAC1 and VPAC2 receptors. It has been studied for its potential role in protecting against neurodegenerative conditions and enhancing cognitive function. [1]

• Immune Regulation:

  Research suggests VIP exerts immunomodulatory effects by regulating cytokine production and inhibiting pro-inflammatory pathways. It may help maintain immune system balance and reduce chronic inflammation. [2]

• Gastrointestinal Function:

  VIP is involved in regulating smooth muscle activity, secretion, and motility in the gastrointestinal tract. Its role in maintaining gut homeostasis and integrity has been of significant interest in clinical and preclinical studies. [1]

Reference Citation:

1. Delgado et al., 2002 – VIP prevents dopaminergic neurodegeneration by inhibiting microglial activation Neurobiology of Disease, 11(2), 127-135. PMID: 12626429
2. Delgado, M., et al. (1999). “Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-kappa B and IFN regulatory factor 1 activation.” Journal of Immunology, 162(8), 4685-4696. PubMed