Description

NAD+ Research Topics:

1. Metabolic Health:

   NAD+ plays a crucial role in cellular metabolism, enhancing energy production and mitochondrial function. It supports the conversion of nutrients into cellular energy, which can improve overall metabolic health and combat metabolic disorders such as obesity and type 2 diabetes (PMID: 32694684).

2. Anti-Aging Effects:

   NAD+ levels decline with age, and boosting NAD+ can promote cellular repair, improve DNA repair mechanisms, and support longevity. This can help mitigate an age-related decline in various bodily functions (PMID: 33353981).

3. Cognitive Function:

   NAD+ is essential for brain health, enhancing neuroprotection and cognitive function. It can help prevent neurodegenerative diseases and improve memory and learning capabilities (PMID: 34530866).

4. Cardiovascular Health:

   NAD+ helps in maintaining cardiovascular health by supporting endothelial function and reducing oxidative stress, which can lower the risk of cardiovascular diseases (PMID: 34843394).

5. Immunoregulation:

   NAD+ contributes to the regulation of the immune system, enhancing the body’s ability to fight infections and reduce inflammation (PMID: 33384409).

Peer-Reviewed Studies

• Preclinical and clinical evidence of NAD⁺ precursors in health, disease, and ageing.

Reiten, O. K., Wilvang, M. A., Mitchell, S. J., Hu, Z., & Fang, E. F. (2021). Preclinical and clinical evidence of NAD⁺ precursors in health, disease, and ageing. Mechanisms of ageing and development, 199, 111567. https://doi.org/10.1016/j.mad.2021.11156

• NAD⁺ homeostasis in human health and disease.

Zapata-Pérez, R., Wanders, R. J. A., van Karnebeek, C. D. M., & Houtkooper, R. H. (2021). NAD⁺ homeostasis in human health and disease. EMBO molecular medicine, 13(7), e13943. https://doi.org/10.15252/emmm.202113943

Structure

Sequence: N/A
Molecular Formula: C21H21N1014P2 Molecular Weight: 663.43 g/mol
PubChem CID: 925
CAS Number: 53-84-9
Synonyms: nicotinamide adenine dinucleotide, beta-NAO, NAO, Endopride