Description

Gonadorelin Research Topics:

1. Improves Fertility:

   Gonadorelin stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are crucial for ovulation in women and spermatogenesis in men. This makes it effective in treating infertility and hormonal imbalances.​ (PMID: 36338812)​

2. Treats Hypogonadism:

   It is used to treat conditions like hypogonadism by boosting testosterone production in men, which helps restore normal testicular function and improves sperm production.​ (PMID: 32445446)​

3. Restore Hormonal Balance:

   By stimulating natural hormone production, Gonadorelin can help in the regulation of menstrual cycles in women and treat conditions like amenorrhea. (PMID: 3103350)​

Peer-Reviewed Studies

• LH and FSH response of Holstein heifers to fertirelin acetate, gonadorelin, and buserelin. Chenault, J. R., Kratzer, D. D., Rzepkowski, R. A., & Goodwin, M. C. (1990). Theriogenology, 34(1), 81-98.

• Neoadjuvant gonadotropin-releasing hormone therapy before surgery may improve the fertility index in undescended testes: a prospective randomized trial. Schwentner, C., Oswald, J., Kreczy, A., Lunacek, A., Bartsch, G., Deibl, M., & Radmayr, C. (2005). The Journal of Urology, 173(3), 974-977.

Structure

Source: PubChem

Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro­Gly
Molecular Formula: C55H15N11013
Molecular Weight: 1182.311 g/mol
PubChem CID: 638793
CAS Number: 9034-40-6
Synonyms: Growth Hormone Releasing Factor, Somatocrinin, Somatoliberin